Under normal conditions, the cerebrospinal fluid (CSF) in adults should not contain any white blood cells (WBCs) or only a small number of them (less than 5 cells per microliter). The absence or low number of WBCs in the CSF is an indication that there is no inflammation or infection in the central nervous system.
However, the presence of elevated WBCs in the CSF (called pleocytosis) can be a sign of various conditions, such as meningitis, encephalitis, or other infections or inflammatory disorders of the brain or spinal cord. The specific number of WBCs that would be considered abnormal or indicative of a particular condition can vary depending on the underlying cause and other factors, such as the patient's age and medical history. A healthcare provider can interpret CSF test results and provide a diagnosis based on the individual's specific situation.
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Normally, there should be no white blood cells (WBCs) present in the cerebrospinal fluid (CSF) of healthy adults. CSF is a clear and colorless liquid that bathes the brain and spinal cord, and it is normally free of cells or contains only a few lymphocytes (a type of white blood cell) that are thought to originate from the normal circulation of lymphocytes through the central nervous system.
However, the presence of white blood cells in the CSF can be an indication of infection, inflammation, or other neurological conditions.
The normal range for CSF WBC counts varies depending on the laboratory that performs the analysis, but typically, any detectable level of white blood cells in the CSF may be considered abnormal and may warrant further investigation by a healthcare provider.
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