what is the best definition of off-label use? a. a placebo treatment method, where a patient is given a placebo drug that has the label of a real drug b. a drug that is being clinically tested, and is not yet labelled c. a drug being used in a manner outside of the specifications on the prescription d. a drug being used in a manner that is not approved by the fda

Answers

Answer 1

Answer:

The term off-label drug use (OLDU) is used extensively in the medical literature, continuing medical education exercises, and the media. Yet, we propose that many health care professionals have an underappreciation of its definition, prevalence, and implications. This article introduces and answers 10 questions regarding OLDU in an effort to clarify the practice's meaning, breadth of application, acceptance, and liabilities. Off-label drug use involves prescribing medications for indications, or using a dosage or dosage form, that have not been approved by the US Food and Drug Administration. Since the Food and Drug Administration does not regulate the practice of medicine, OLDU has become common. It occurs in every specialty of medicine, but it may be more common in areas of medicine in which the patient population is less likely to be included in clinical trials (eg, pediatric, pregnant, or psychiatric patients). Pharmaceutical companies are not allowed to promote their medications for an off-label use, which has lead to several large settlements for illegal marketing. To limit liability, physicians should prescribe medications only for indications that they believe are in the best interest of the patient. In addition, health care professionals should educate themselves about OLDU to weigh the risks and benefits and provide the best possible care for their patients.


Related Questions

One of the goals of psychology is to predict future behavior or mental processes. Which of the following scenar
best illustrates this goal?
A The psychologist measures Michael's heart rate and bodily functions to better describe his
behavior
B. The psychologist helps Michael develop strategies to manage his anxiety levels so he can
focus on the game
C. The psychologist tells Michael that his basketball performance will improve when his anxiety
levels are moderated
D. After careful research, the psychologist explains that Michael's intense feelings of anxiety are
hindering his basketball performance.

Answers

Answer:

The answer is C

Explanation:

I saw it on quizlet taking test now

The psychologist tells Michael that his basketball performance will improve when his anxiety levels are moderated is best illustrates this goal.

Who are pshychologist?

A psychologist is a specialist in the field of psychology who investigates behavior as well as mental states, perceptual, cognitive, emotional, and social processes. They frequently experiment with, observe, and interpret how people interact with one another and their surroundings as part of their work.

A psychology bachelor's degree is typically followed by a psychology master's or doctoral degree for psychologists. Unlike psychiatric doctors and psychiatric nurse practitioners, psychologists typically cannot prescribe medication.

Unlike psychiatrists, who typically lack training in psychological testing, psychologists undergo significant training in psychological testing, scoring, interpretation, and reporting.

Therefore, The psychologist tells Michael that his basketball performance will improve when his anxiety levels are moderated is best illustrates this goal.

To learn more about Psychologist, refer to the link:

https://brainly.com/question/3833605

#SPJ2

Which organization awards a seal of acceptance classification to products that are safe and affective for self care?s

Answers

Answer:

ADA

Explanation:

Studying medical terminology can help someone pursuing a career in ________ because they will need to be familiar with the sound and spelling of words that are directed to them.

Answers

Answer:

medical transcription

Explanation:

Answer:

medical transcription

Explanation:

Edge 2023

What denotes the back surface of the body or nearer to the back

Answers

Answer:Dorsal

Explanation:

HOW MANY WORD ROOTS ARE LISTED IN THIS TERM? HYPERTROPHIC
CARDIOMYOPATHY
1?
4?
2?
3?

Answers

Answer:

3

Explanation:

1. Cardio

2. Hyper

3. Trophy

pharmacokinetics is the study of a. what reaction a drug has on the body b. the various uses that one drug may serve within the body c. the reaction of drug when taken with other drugs d. what reaction the body has on a drug

Answers

Answer:

Drug-drug interactions (DDIs) are one of the commonest causes of medication error in developed countries, particularly in the elderly due to poly-therapy, with a prevalence of 20-40%. In particular, poly-therapy increases the complexity of therapeutic management and thereby the risk of clinically important DDIs, which can both induce the development of adverse drug reactions or reduce the clinical efficacy. DDIs can be classify into two main groups: pharmacokinetic and pharmacodynamic. In this review, using Medline, PubMed, Embase, Cochrane library and Reference lists we searched articles published until June 30 2012, and we described the mechanism of pharmacokinetic DDIs focusing the interest on their clinical implications.

Keywords: Absorption, adverse drug reaction, distribution, drug-drug interactions, excretion, metabolism, poly-therapy

Sofiya is learning about the human brain. Her teacher asks to her identify a part of the brain's central core. Which of the following should she choose?

Answers

Answer:

This question lacks options, options are:

A) cerebral cortex

B) cerebellum

C) hypothalamus

D) spinal cord

The correct answer is B.

Explanation:

Brain's central cored is considered our primitive brain and defined as a hierarchical cognitive organization, it is responsible for carrying out the most basic functions and those unconscious and involuntary behaviors, it is formed by the reticular system, the cerebellum, the basal ganglia and the brain stem. The cerebellum is a motor organ located in the posterior fossa, closely related to the brain stem which is responsible for controlling balance, constantly monitoring the feedback of the muscles to coordinate their location, movement and tension.

Key characteristic of systematic review is that it contains meta analysis. True or false

Answers

Answer:

False

Explanation:

Meta-analysis does not have to be necessarily included in a systematic review.

The main characteristic of a systematic review is that it analyzes a question using explicit and systematic methods that will help to select and analyze data from studies. The use of statistical methods, which are also known, as meta-analysis is optional, but it can help during the analysis.




"There is no life outside this solar system, and nothing you can say will change that fact!" Which criterion of critical thinking does this person lack?

Answers

Answer:

"Critical thinking requires an open mind."

Explanation:

Critical thinking is the type of thinking in which the person analyzes and evaluates the facts in a detailed manner. The analyzes then help in the formation of the judgment related to the given facts. Critical thinking aims towards a specific goal which includes the explanation of the facts, methods, and process of extracting the conclusion. It requires an acceptance of a broad mindset to accept certain facts and then evaluate from the given facts and details.

In the given excerpt, the person making such a remark about the solar system lacks the openness and accepting mindset. It is because of this reason that he exerts his thoughts and names it to be a fact.

What is the kneecap to the ankle

Answers

Answer:

The second largest bone in the leg and the human body is the tibia

Nursing-maintaining a professional distance

Answers

Yes? Wait what’s the question here, that looks more like an answer

Type ________ diabetes is ideally treated with diet and exercise, along with the administration of oral hypoglycemic medications to help control the blood sugar levels.

Answers

Type two diabetes is ideally treated with diet and exercise, along with the administration of oral hypoglycemic medications to help control the blood sugar levels.


Hope this helps :)

Type 2 diabetes is ideally treated with diet and exercise, along with the administration of oral hypoglycemic medications to help control the blood sugar levels.

What is type 2 diabetes?

Diabetes type 2 is a condition that affects the way in which the body controls and uses sugar (also known as glucose) as a fuel. Because of this illness that lasts for a long time (chronic), there is an excessive amount of sugar circulating in the bloodstream. In the long run, having high blood sugar levels can cause problems with the circulatory system, the nervous system, and the immune system.

Diabetes type 2 is primarily caused by two issues that are interrelated. The cells that make up muscle, fat, and the liver all become resistant to the effects of insulin. Due to the abnormal interaction that these cells have with insulin, they are unable to take in the required amount of sugar.

Diet, exercise, and the possible use of oral hypoglycemic drugs are the three components of an ideal treatment plan for type two diabetes. These components work together to help keep blood sugar levels under control.

Learn more about diabetes, here:

https://brainly.com/question/14264614

#SPJ5

The part of HIPAA that specifically deals with the confidentiality of patient records is known as the

Answers

The HIPPA Privacy rule

Answer:

privacy rule

Explanation:

A formula calls for 0.235 L of an oil whose specific gravity is 0.950. How many pounds will the oil weigh? Round to the nearest hundredth.

Answers

730 :) good luck on your assignment

7. Iwhich of the following examples does NOT demonstrate plasticity?
O pianists who have an enlarged auditory cortex area that encodes piano sounds
O a blind person using echolocation to navigate his environment
O ballerinas who experience neural changes that improve their performance
O a scientist discovering how long it takes a neural impulse to travel a neural pathway

Answers

Answer:

d

Explanation:

hope this helped

The statement 'a scientist discovering how long it takes a neural impulse to travel a neural pathway' does NOT demonstrate plasticity.

Plasticity refers to the ability that an organism has to change (adapt) in response to environmental conditions.

The phenotype can be defined as all observable characteristics of an organism.

The phenotypic plasticity allows an organism to face environmental changes, increasing thus its adaptive fitness.

In conclusion, the statement 'a scientist discovering how long it takes a neural impulse to travel a neural pathway' does NOT demonstrate plasticity.

Learn more in:

https://brainly.com/question/4052063?referrer=searchResults

Which is an activity that will build muscle endurance? (5 points) Group of answer choices a.Yoga b. Gymnastics c. Powerlifting d. Swimming

Answers

Answer:

c. powerlifting

Explanation:

Answer:

Swimming

Explanation:

took the test

10. What must first be done before treating an animal for a behavioral problem? O A. Ruling out a medical problem O B. Giving the animal a behavioral exam C. Changing the environment OD. Prescribing medication​

Answers

Answer:

The correct answer is - option A.  Ruling out a medical problem

Explanation:

what is one of benefits the pharmacy technician may receive for the subscription fee they pay to a pharmacy association? a. live webinars and CE seminars b. more CE hours c. access to free drug samples d. the chance to publish articles to reputable websites

Answers

Answer:

a?

Explanation:

How is the fluid level measured in a syringe

Answers

It is measure by mL, the bigger the syringe the more mL it will be

Which of the following is not a function of blood

A) homeostatic regulation
B) transport of metabolic wastes
C) hormone production
D) protection from infection

Answers

Answer:

C) hormone production

Based on the known functions of blood, the function not performed by the blood from the given options is hormone production, option C.

What is the role of blood in the body?

Blood is a red-coloured fluid constantly circulating in the body, which provides the body with nutrition, oxygen, and waste removal.

Blood performs various functions in the body which includes:

Transport of nutrients,Transport of oxygen,Waste removal.Maintenance and regulation of homeostasisProtection from infection

However, the role of production of hormones is the function of glands in the body.

Therefore, the function not performed by the blood from the given options is hormone production, option C.

Learn more about the functions of blood at: https://brainly.com/question/4541338

which of the following is information that can be found in the pharmacy technician's pocket drug reference book? a. drug manufacturer details b. drug side effects c. drug expiration dates d. information on the trial studies done on the medication

Answers

Drug expiration dates is a type of information that can be found in the pharmacy technician's pocket drug reference book.

What is the pharmacy technician's pocket drug reference book?

The pharmacy technician's pocket drug reference book is a widely used book in the pharmacy field.

This book has been a reference material for pharmacists and biochemists for many years.

The pharmacy technician's pocket drug reference book is fundamental because it includes generic and non-generic names for all therapeutic drugs that have already been approved by the U.S. Food and Drug Administration.

In conclusion, drug expiration dates is a type of information that can be found in the pharmacy technician's pocket drug reference book.

Learn more about the drug reference books here:

https://brainly.com/question/12858359

#SPJ1

All anatomical terms have a _ _ _ _ _ _ _ _ _ point which is called the _ _ _ _ _ _ _ _ _ _ position. This is a_ _ _ _ position where you _ _ _ _ _ up, head straight and _ _ _ _ by your _ _ _ _, with the palm of your _ _ _ _ _ facing forward.

Answers

All anatomical terms have a "reference" point which is called the "anatomical" position. This is a "body" position where you "stand" up, head straight and "arms" by your "side" with the palm of your "hands" facing forward.

All anatomical terms have a reference point which is called the anatomical position. This is a "body" position where you stand up, head straight and arms by your side with the palm of your hands facing forward.

What is anatomical term ?

The study of the structure of the human body and other animal called as anatomy.

This term will allow health care professionals to communicate with other professional accurately by discussing the affected body parts or disorder.  

If a person is in a standing position, the term defined in the reference called anatomical position like both feet pointing forwards, arms down to the side with palms forward.

Some of the anatomical directional terms are anatomical Directional Terms.

For example, Anterior refers to In front of, Posterior is After, behind, following, Distal is farther from the origin, Proximal is Near, lateral, vertical, horizontal, Dorsal, ventral etc.

Learn more about anatomy, here:

https://brainly.com/question/21190730

#SPJ2

The nurse is admitting a military veteran to the unit following an amputation of the lower extremity. Which of the following statements by the nurse would supply the most information about the patient's psychiatric well-being?

Answers

Answer:

tell where he was stationed, how long, how harsh the living environments were and what happened to make have an amputation and his BP

Other Questions
Harvey mixes two liquids. Which observation of the new mixture most likely indicates a precipitate is O A. a cloudy appearance OB. a bubble formation OC. a change in color O D. a change in odor ESTUDIANTE: Abro el saco de dormir?INSTRUCTOR: S, _[blank 1]_.ESTUDIANTE: Hago una fogata?INSTRUCTOR: S, _[blank 2]_.ESTUDIANTE: Uso los fsforos para hacer la fogata?INSTRUCTOR: S, _[blank 3]_.ESTUDIANTE: Guardo los remos?INSTRUCTOR: S,_[blank 4]_.Empareja los espacios en blanco con los mandatos correctos.Select an optiongurdeloselosgurdelosbralabralohgala The Civil Service Exam was designed to make sure A. nobles were following Buddhist practicesB. bureaucrats were qualified for their jobs.C. soldiers had the best military training availableD. peasants had the latest agricultural technologies. Which problem can be represented by the equation 100x+50=710?A coin bank can hold 710 coins. There are 50 coins in the bank. A student puts in 100 coins per week. How many weeks until the bank is full?A coin bank can hold 100 coins. There are 50 coins in the bank. A student puts in 710 coins per week. How many weeks until the bank is full?A coin bank can hold 100 coins. There are 710 coins in the bank. A student puts in 50 coins per week. How many weeks until the bank is full?A coin bank can hold 710 coins. There are 100 coins in the bank. A student puts in 50 coins per week. How many weeks until the bank is full? Can you help me with the question listed in the picture below? Please and thank you. Will mark BRAINLIEST!!! :) What does the author convey through this analogy?Life is like an echo. What you send out comes back.A. The satisfaction people get from life depends on their personal actions.B. People need to listen to themselves to be truly heard by others.C. The struggle for fairness can be seen in what people do throughout their lives.D. Reflecting on past decisions can help people take the right steps in the future. Solve 3x - x + 2 = 12.O 1) 5O 2) 40 3 74) 5 A certain substance X has a normal freezing point of 3.1C and a molal freezing point depression constant =Kf6.23Ckgmol1. Calculate the freezing point of a solution made of 12.3g of urea NH22CO dissolved in 300.g of X. Be sure your answer has the correct number of significant digits. Questions for Hydration: Why its so Important1) What percentage of your body does water make up?2) What 5 functions does water serve in our bodies?3) In what 3 ways do you lose water from your body every day?4) What percentage of your daily water intake do you receive from eating?5) What happens at about 1% hydration loss?6) Why does urine become darker in the body?7) How many total fluid Ounces of water should you be drinking each day (yes you need to domath)?8) True or False. You can drink too much water?9) When is it recommended to drink sports drinks and what is the ingredient in them that makesthem more beneficial?10) What is the problem with juices and sports drinks?11) How much water do you drink every day? What are the points of intersection of the following functions? F(x)=3x+6 and g(x)=2x^2-3 Most investors approach risky investments byO investing the same way that they do with safer investments.O investing more money in the stock of unknown companies.O investing less money in low- and medium-risk investments.O investing less money in high-risk investments. According to the American music industry, the length of a song is normally distributed with a mean of 240 seconds and standard deviation thirty seconds. Suppose a random sample of fifteen songs is selected from the morning program. what is the probability that the length of the song is between 225 and 260 seconds long? Because a gas has no definite volume or shape, in what way does it take up space? (2 points)Group of answer choicesBy taking the volume of a solidBy taking the volume of a liquidBy taking the shape of its containerBy taking the volume of its container What is your opinion about heroes ? Solve 1-4 to be mark brainiest and show your work! solve for x: 7^(3x+7)=7^(-8x-4) Select the correct answer from each drop-down menu.Read the passage and choose the correct word to complete the sentences that follow:Eventually, the English throne was brought back to power. Despite the return to normalcy, the second half of the seventeenth century was full ofconstant religious and political upheaval. Although anti-Catholicism was widespread, King Charles Il who had Catholic leanings, urged tolerance.In 1688forced out Charles's successor, the Catholic King James II, and brought Protestantism back to Great Britain.When compared to the previous two centuries, the eighteenth century was far more Which statements apply to a certificate of deposit (CD)? Check all that apply.It is always purchased as a short-term investment.It can be purchased from a banking institution.It is ahvays purchased as a long-term investment.It can be purchased for almost any amount.It is purchased through an individual's employer. reptiles are ovoviviparous? these days more and more appliances are talking to each other and with the internet. How will all this talk help in the development of AI systems