Engineering

Learn how changes in binding free energy affect binding and the ratio of unbound and bound molecules. Similar to the lecture, our example is a drug molecule D and a drug target enzyme E. The drug target enzyme E is commonly found in concentrations [E]tot of 250 nM, i.e. 2.5 x 10-7 mol/l. The drug D binds to E to form the complex ED with a dissociation constant of KD = 1.30 M (i.e. 1.30 x 10-6). The dissociation constant has been determined at room temperature, i.e. for T = 298.15 K.In order to estimate the effectivity of the drug D, calculate the ratio of the concentration of the free, unbound drug molecules [D] and the bound complex [ED], i.e. [D]/[ED], for the conditions described in part B. Provide your answer with 3 significant figures.The margin of error is 2%.
1 Answer
wind tunnel tests yield the following data for lift and pitch moment about the half-chord line of a given wing: cl cm1/2 0.4 0.2 0.8 0.3 1. find hac. 2. find cmac . 3. find hcp when cl
1 Answer
1. A steel container expands in volume 1% when the pressure with in it is increased by 70Mpa. At standard pressure, it holds 8kg of water; =1000kg/m3. For K=2.05Gpa, when it is filled, how many kilograms of water must be added to increase the pressure to 70Mpa (gage)?
1 Answer
Draw shear Force and bending moment diagram for the beam given below.
1 Answer
how to make demultiplexer using or gates?
1 Answer
Consider the following instance variable and method.private int[] numbers;/* Precondition: numbers contains int values in no particular order. /public int mystery(int num){for (int k = numbers.length 1; k >= 0; k){if (numbers[k] < num){return k;}}return -1;}Which of the following best describes the contents of numbers after the following statement has been executed?int m = mystery(n);a. All values in positions 0 through m are less than n.b. All values in positions m+1 through numbers.length-1 are less than n.c. All values in positions m+1 through numbers.length-1 are greater than or equal to n.d. The smallest value is at position m.e. The largest value that is smaller than n is at position m.
1 Answer
a personal fall arrest system must be secured properly to a
1 Answer
which of the following statements related to the regenerator are true? multiple select question. a regenerator with a high effectiveness can save on the amount of fuel used.
1 Answer
1. A wood board is one of a dozen different parts in a homemade robot kit. The width, depth, and height dimensions of the board are 7. 5 x 14 x 1. 75 inches, respectively. The board is made from southern yellow pine, which has an air dry weight density of. 025 lb/in. 3. A. What is the volume of the wood board? Precision = 0. 0
1 Answer
you genetically engineer a strain of yarrowia lipolytica to produce vitamin c. which of the following will be needed for the yeast to produce this vitamin?
1 Answer
Use your knowledge about how basalt provinces form to place the following events in sequence from oldest to youngest.
1 Answer
technician a says all differentials are vented. technician b says that a clogged vent can cause the rear axle seal to leak. which technician
1 Answer
write a method that takes 2 coordinates in a 2d plane (x, y coordinates) and computes the distance between these two points, according to the distance formula, which is as follows: distance formula this method must be named distance() and it must have 4 int parameters. the first parameter will be the x-coordinate of the first point, the second parameter will be the y-coordinate of the first point, the third parameter will be the x-coordinate of the second point, and the fourth parameter will be the y-coordinate of the second point. this method must return a double. calling distance(0, 5, 0, 0) would return 5.0. you can call your method in the program's main method so you can test whether it works, but you must remove or comment out the main method before checking your code for a score.
1 Answer
questiona test car and its driver, with a combined mass of 600 kg, are moving along a straight, horizontal track when a malfunction causes the tires to stop rotating. the car skids to a halt with constant acceleration, leaving skid marks on the road during the whole time it skids. which two of the following measurements, taken together, would allow engineers to find the total mechanical energy dissipated during the skid? select two answers.
1 Answer
Consider a simple pendulum and compute the magnitude of the restoring force if the mass of the pendulum is 2 kg and the length of the pendulum is 0.5 m. Assume the pendulum is at the surface of the earth at sea level.
1 Answer
FILL IN THE BLANK When a non-motor-operated electrical appliance lacks an overcurrent protective device rating, NEC 422.11(E) states that the branch circuit overcurrent protection shall be ____.
1 Answer
Problem 2. How many bits are needed to store the following data? (8 points) a. String of 6 ASCII characters b. Decimal number equal to 27 c. Binary number equal to 1010101 d. One Kilobyte (KB) of data
1 Answer
Intro to JAVAIf you have a class called IceScraper nested within the class Car, which of these would be the correct way to instantiate an IceScraper object?a) Car.IceScraper ice_scraper = new Car.IceScraper();b)IceScraper ice_scraper = new Car.IceScraper();c) IceScraper.Car ice_scraper = new IceScraper.Car();d) Car.IceScraper ice_scraper = Car.new IceScraper();
1 Answer
given the wheelbase of the car 138.8 inches, trackwidth 75 inches and loads on tires as follows. determine the longitudinal cg location in inches measured from the front wheel,
1 Answer
Which of the following statements are true for artificial intelligence (AI)? [Choose all that apply]AI focuses on the broad idea of making a system execute a taskMachine Learning or ML is a subset of AIAI learns on its own without any input dataA self-driving car is an example of AI
1 Answer
For each of the four types of organizations shown, rate the importance of each factor in terms of making location decisions using L low importance, M moderate importance, and H high importance.
1 Answer
what is situations would it be possible to use a utp cable standard such as 1000base-cx instead of a fiber-optic cable standard such as 1000base-lx or 1000base-t?
1 Answer
determine each component within the microphone-to-multitrack signal flow in your system, and present it in the form of a block diagram.
1 Answer
if the handle of an installed motor starter is in the center position, what condition does this indicate?
1 Answer